Defining the risks associated with
diabetes mellitus in patients undergoing
penile prosthesis implantation remains controversial. Our study aims to assess whether preoperative
hemoglobin a1c and preoperative
blood glucose levels are associated with an increased risk for postoperative
infection in diabetic men. We performed a retrospective review of 932 diabetic patients undergoing primary
penile prosthesis implantation from 18 high-volume
penile prosthesis implantation surgeons throughout the United States, Germany, Belgium, and South Korea. Preoperative
hemoglobin a1c and
blood glucose levels within 6 h of surgery were collected and assessed in univariate and multivariate models for correlation with postoperative
infection, revision, and explantation rates. The primary outcome is postoperative
infection and the secondary outcomes are postoperative revision and explantation. In all, 875 patients were included in the final analysis. There were no associations between preoperative
blood glucose levels or
hemoglobin a1c levels and postoperative
infection rates; p = 0.220 and p = 0.598, respectively. On multivariate analysis, a history of
diabetes-related complications was a significant predictor of higher revision rates (p = 0.034), but was nonsignificant for
infection or explantation rates. We conclude preoperative
blood glucose levels and
hemoglobin a1c levels are not associated with an increased risk for postoperative
infection, revision, or explantation in diabetic men undergoing
penile prosthesis implantation.