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Tumor-targeted near-infrared fluorophore for fluorescence-guided phototherapy.

Abstract
A tumor-targeted near-infrared (NIR) fluorophore CA800SO3 was developed for fluorescence-guided phototherapy. This new type of NIR fluorophore showed high tumor targetability based on the structure-inherent targeting approach. This fluorophore generated sufficient hyperthermia and reactive oxygen species (ROS) simultaneously for synergistic cancer phototherapy, induced by an 808 nm laser irradiation.
AuthorsMin Ho Park, Gayoung Jo, Eun Jeong Kim, Jin Seok Jung, Hoon Hyun
JournalChemical communications (Cambridge, England) (Chem Commun (Camb)) Vol. 56 Issue 30 Pg. 4180-4183 (Apr 14 2020) ISSN: 1364-548X [Electronic] England
PMID32167112 (Publication Type: Journal Article)
Chemical References
  • Fluorescent Dyes
Topics
  • Animals
  • Cell Line, Tumor
  • Fluorescence
  • Fluorescent Dyes (chemical synthesis, chemistry)
  • Humans
  • Infrared Rays
  • Mice
  • Molecular Structure
  • Neoplasms (diagnostic imaging, therapy)
  • Neoplasms, Experimental (diagnostic imaging, therapy)
  • Particle Size
  • Phototherapy
  • Surface Properties

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