Abstract |
A tumor-targeted near-infrared (NIR) fluorophore CA800SO3 was developed for fluorescence-guided phototherapy. This new type of NIR fluorophore showed high tumor targetability based on the structure-inherent targeting approach. This fluorophore generated sufficient hyperthermia and reactive oxygen species (ROS) simultaneously for synergistic cancer phototherapy, induced by an 808 nm laser irradiation.
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Authors | Min Ho Park, Gayoung Jo, Eun Jeong Kim, Jin Seok Jung, Hoon Hyun |
Journal | Chemical communications (Cambridge, England)
(Chem Commun (Camb))
Vol. 56
Issue 30
Pg. 4180-4183
(Apr 14 2020)
ISSN: 1364-548X [Electronic] England |
PMID | 32167112
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Cell Line, Tumor
- Fluorescence
- Fluorescent Dyes
(chemical synthesis, chemistry)
- Humans
- Infrared Rays
- Mice
- Molecular Structure
- Neoplasms
(diagnostic imaging, therapy)
- Neoplasms, Experimental
(diagnostic imaging, therapy)
- Particle Size
- Phototherapy
- Surface Properties
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