Abstract | PURPOSE: MATERIALS AND METHODS: Using claims data from Taiwan's National Health Insurance Research Database, a total of 1077 patients who received ECMO and either continuous venovenous hemofiltration (CVVH) or continuous venovenous hemodialysis ( CVVHD) for AKI were identified. Inverse probability of treatment weighting was applied using propensity scores to balance the baseline covariates of the two groups. The primary outcome was in-hospital morality. RESULTS: We identified 1077 patients (mean age 57.9; 71.8% men). Postcardiotomy shock (49.2%) was the most frequently reported indication for ECMO. The CVVH group had a lower risk of in-hospital mortality (68.4% vs. 76.9%; odds ratio 0.65; 95% confidence interval [CI] 0.50-0.85) compared with the CVVHD group. The CVVH group also had a shorter mean ICU stay compared with the CVVHD group (mean difference -4.59 days, 95% CI -9.15 to -0.03 days). CONCLUSION: Our results suggest that compared with CVVHD, CVVH may be associated with a lower risk of in-hospital mortality in patients with AKI who receive ECMO.
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Authors | Cheng-Chia Lee, Shao-Wei Chen, Ya-Lien Cheng, Pei-Chun Fan, Tsung-Yu Tsai, Ming-Jen Chan, Su-Wei Chang, Hsiang-Hao Hsu, Ji-Tseng Fang, Chih-Hsiang Chang |
Journal | Journal of critical care
(J Crit Care)
Vol. 57
Pg. 102-107
(06 2020)
ISSN: 1557-8615 [Electronic] United States |
PMID | 32088523
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2020 Elsevier Inc. All rights reserved. |
Topics |
- Acute Kidney Injury
(therapy)
- Adult
- Aged
- Continuous Renal Replacement Therapy
(methods)
- Extracorporeal Membrane Oxygenation
(methods)
- Female
- Hemofiltration
- Hospital Mortality
- Humans
- Inflammation
- Male
- Middle Aged
- Odds Ratio
- Registries
- Taiwan
(epidemiology)
- Treatment Outcome
- Young Adult
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