Abstract | BACKGROUND: CASE PRESENTATION: Our patient was a 60-year-old Caucasian man with bone and lung metastases from renal cell carcinoma. He developed leptomeningeal metastasis and progression of bone and lung lesions after only 2 months of his first-line treatment. He was then treated with nivolumab in second-line setting and experienced a rapid improvement of cancer-related symptoms, complete remission of leptomeningeal and lung lesions, and increased bone mineral density in bone metastasis. The patient did not experience any drug-related toxicity. CONCLUSIONS:
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Authors | Lucia Bonomi, Anna Cecilia Bettini, Ermenegildo Arnoldi, Alessandra Chirco, Laura Ghilardi, Ornella Manara, Marco Roscigno, Luigi Filippo Da Pozzo, Carlo Alberto Tondini |
Journal | Tumori
(Tumori)
Vol. 106
Issue 6
Pg. NP76-NP78
(Dec 2020)
ISSN: 2038-2529 [Electronic] United States |
PMID | 32041500
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antineoplastic Agents, Immunological
- Nivolumab
|
Topics |
- Antineoplastic Agents, Immunological
(administration & dosage, adverse effects, therapeutic use)
- Carcinoma, Renal Cell
(pathology)
- Combined Modality Therapy
- Humans
- Kidney Neoplasms
(pathology)
- Magnetic Resonance Imaging
- Male
- Meningeal Neoplasms
(diagnosis, drug therapy, secondary)
- Middle Aged
- Nivolumab
(administration & dosage, adverse effects, therapeutic use)
- Tomography, X-Ray Computed
- Treatment Outcome
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