Necrobiosis Lipoidica Mimicking Cutaneous Sarcoidosis Finally Treated With an Intralesional Injection of Corticosteroid: A Case Report

Abstract

BACKGROUND: Necrobiosis lipoidica (NL) and sarcoidosis are granulomatous disorders with an unknown pathogenesis. They may coexist in the same patient, which suggests a possible overlap between these diseases among shared granulomatous inflammatory pathways. Case Presentation: This study presents the case of a non-diabetic 52-year-old woman who presented with red-yellowish border plaques on the face and upper extremities previously diagnosed as sarcoidosis. After 13 years of inappropriate treatment, histopathological findings consistent with the clinical and para-clinical examination suggested the diagnosis of NL. After treatment with an intralesional injection of steroids, significant improvement was observed, and no recurrent lesions were found. CONCLUSION: Necrobiosis lipoidica may mimic cutaneous sarcoidosis. Prompt recognition and treatment of NL can be helpful for managing the disease. J Drugs Dermatol. 2020;19(1):92-94. doi:10.36849/JDD.2020.4675

• Authors: Mohamad Goldust, Ghasem Rahmatpour Rokni, Jeffrey M. Weinberg, Leon Kircik, Martine Bagot
• Journal: Journal of drugs in dermatology : JDD (J Drugs Dermatol) Vol. 19 Issue 1 Pg. 92-94 (Jan 01 2020) ISSN: 1545-9616 [Print] United States
• PMID: 32023016 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids

Topics

• Female
• Glucocorticoids (administration & dosage)
• Humans
• Injections, Intralesional
• Middle Aged
• Necrobiosis Lipoidica (diagnosis, drug therapy, pathology)
• Sarcoidosis (diagnosis)