Abstract | BACKGROUND: The peritonitis rate among children treated with peritoneal dialysis (PD) has not been widely reported in Saudi Arabia. The study aim was to estimate the peritonitis rate per patient-year and investigate the factors associated with higher peritonitis rates in a sample of PD children at King Abdullah Specialist Children's Hospital-Riyadh (KASCH-R), Saudi Arabia. METHODS: This retrospective cohort study included 27 PD children treated between September 2007 and December 2017 at KASCH-R. We recorded the children's demographic and clinical data, and the frequency of peritonitis. RESULTS: The 27 PD children reviewed (63% girls; mean age = 7.32 years old; range, 1-14 years), resulted in 86 peritonitis diagnoses in which the overall recurrence rate (in at least one episode) was 58/86 (67.4%) with a 95% confidence interval (CI), 56.5 to 77.2%. The rate of peritonitis episodes per patient-year was 0.76 (1 episode per 1.31 patient-year). The generalized Poisson model identified older children (age > 10 years) (adjusted rate ratios [aRR] = 7.273, 95% CI: 1.562-33.860), congenital nephrosis (aRR = 4.677, 95% CI: 1.443-15.155), height below 3rd percentile (aRR = 4.689, 95% CI: 1.874-11.735), weight below 3rd percentile (aRR = 5.388, 95% CI: 1.678-17.302), low albumin level (aRR = 4.041, 95% CI: 2.053-7.956), two-week duration of antibiotic therapy (aRR = 2.947, 95% CI: 1.163-7.468), which were independently associated with a high peritonitis rate. CONCLUSIONS:
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Authors | Khamisa Al Mokali, Zahra Al Sannaa, Faten Al Mutairi, Anwar E Ahmed |
Journal | BMC pediatrics
(BMC Pediatr)
Vol. 20
Issue 1
Pg. 42
(01 29 2020)
ISSN: 1471-2431 [Electronic] England |
PMID | 31996157
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Age Factors
- Anti-Bacterial Agents
(administration & dosage)
- Body Size
- Child
- Child, Preschool
- Female
- Humans
- Infant
- Kidney Failure, Chronic
(therapy)
- Male
- Nephrosis
(congenital)
- Peritoneal Dialysis
(adverse effects)
- Peritonitis
(epidemiology, etiology)
- Poisson Distribution
- Retrospective Studies
- Risk Factors
- Saudi Arabia
(epidemiology)
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