Interventional endoscopic ultrasound for pancreatic neuroendocrine neoplasms.

Abstract

The proximity of the endoscopic ultrasound (EUS) transducer to the pancreas and the possibility to place needles or other accessories into a target located adjacent to the wall of the GI tract have encouraged researchers to develop various EUS-guided local treatments directed towards pancreatic neuroendocrine neoplasms (PanNENs). The use of pre-operative EUS-guided tattooing or fiducial marker placement to facilitate intraoperative tumor localization has proven effective in reducing operative time of laparoscopic surgeries. To reduce the mortality and morbidity rates of surgical resection, which is presently the mainstay treatment of PanNENs. EUS-guided loco-regional treatments, such as injection of alcohol and radiofrequency ablation have been proposed and results are hitherto promising. The present paper summarizes currently available data in the field of EUS-guided interventions to pancreatic neuroendocrine tumors, as well as possible future applications.

• Authors: Mihai Rimbaş, Mihaela Horumbă, Gianenrico Rizzatti, Stefano Francesco Crinò, Antonio Gasbarrini, Guido Costamagna, Alberto Larghi
• Journal: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society (Dig Endosc) Vol. 32 Issue 7 Pg. 1031-1041 (Nov 2020) ISSN: 1443-1661 [Electronic] Australia
• PMID: 31995848 (Publication Type: Journal Article, Review)
• Copyright: © 2020 Japan Gastroenterological Endoscopy Society.

Topics

• Endosonography
• Humans
• Laparoscopy
• Pancreatic Neoplasms (diagnostic imaging, surgery)
• Radiofrequency Ablation
• Ultrasonography, Interventional