Abstract | Purpose: Materials and Methods: Between 2007 and 2017, 362 patients who underwent RARC with ECUD or ICUD at multiple tertiary referral institutions were assessed. The primary endpoints were complication rates. The secondary outcomes were perioperative recovery parameters and oncological outcomes including estimated recurrence-free survival (RFS) and recurrence pattern between the 2 groups. Additionally, the complication rates of 2 expert surgeons with experience of >100 RARCs were analyzed. Results: The ICUD group showed lower overall, gastrointestinal, and genitourinary complications (p=0.001, p=0.036, and p=0.036, respectively) than the ECUD group. Concerning perioperative outcomes, the ICUD group had a significantly longer operation time (p=0.002), although recovery parameters such as time to flatus passage, oral intake, and length of hospital stay were significantly shorter in this group (p=0.001, p<0.001, and p<0.001, respectively). There was no difference in oncologic outcomes such as positive margin rate (p=0.944) and 2-year RFS (p=0.496), and in the recurrence pattern between groups. In the comparison of the expert surgeons' complication rates, the major and total complication rates did not show differences (p=0.814 and p=0.102, respectively) while the minor complication rates were lower in the ICUD group (p=0.058). Conclusions: This multi-institutional cohort study demonstrated the benefits of the ICUD approach, as indicated by lower complication rates and better recovery parameters, although the oncological results were similar to those of ECUD.
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Authors | Ji Sung Shim, Tae Gyun Kwon, Koon Ho Rha, Young Goo Lee, Ji Youl Lee, Byong Chang Jeong, Jong Hyun Pyun, Sung Gu Kang, Seok Ho Kang |
Journal | Investigative and clinical urology
(Investig Clin Urol)
Vol. 61
Issue 1
Pg. 11-18
(01 2020)
ISSN: 2466-054X [Electronic] Korea (South) |
PMID | 31942458
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © The Korean Urological Association, 2020. |
Topics |
- Cohort Studies
- Comparative Effectiveness Research
- Cystectomy
(adverse effects, methods, statistics & numerical data)
- Female
- Humans
- Length of Stay
(statistics & numerical data)
- Male
- Margins of Excision
- Middle Aged
- Operative Time
- Postoperative Complications
(diagnosis, epidemiology, etiology)
- Republic of Korea
(epidemiology)
- Robotic Surgical Procedures
(adverse effects, methods, statistics & numerical data)
- Survival Analysis
- Urinary Bladder
(pathology, surgery)
- Urinary Bladder Neoplasms
(epidemiology, pathology, surgery)
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