Honey as the Potential Natural Source of Cholinesterase Inhibitors in Alzheimer's Disease.

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized, among others by abnormal levels of acetyl- and butyrylcholinesterase in the brain. In this study, 47 types of Polish honeys were examined (using colorimetric method) as a source of acetyl- and butyrylcholinesterase inhibitors. The highest potential for AChE inhibition was observed in the case of buckwheat honey (39.51% inhibition), while multi-floral honey showed the highest capacity for BChE inhibition (39.76%). Our study revealed that honeys can be a rich source of cholinesterase inhibitors and therefore may play a role in AD treatment.

• Authors: Ewa Baranowska-Wójcik, Dominik Szwajgier, Anna Winiarska-Mieczan
• Journal: Plant foods for human nutrition (Dordrecht, Netherlands) (Plant Foods Hum Nutr) Vol. 75 Issue 1 Pg. 30-32 (Mar 2020) ISSN: 1573-9104 [Electronic] Netherlands
• PMID: 31925635 (Publication Type: Journal Article)

Chemical References

• Cholinesterase Inhibitors
• Acetylcholinesterase

Topics

• Acetylcholinesterase
• Alzheimer Disease
• Cholinesterase Inhibitors
• Honey
• Humans
• Neurodegenerative Diseases