Abstract | OBJECTIVE: Untreated hydrocephalus poses a significant health risk to children in the developing world. In response to this risk, global neurosurgical efforts have increasingly focused on endoscopic third ventriculostomy with choroid plexus cauterization (ETV/ CPC) in the management of infantile hydrocephalus in low- and middle-income countries (LMICs). Here, the authors report their experience with ETV/ CPC at the Hospital Bernard-Mevs/Project Medishare (HBMPM) in Port-au-Prince, Haiti. METHODS: The authors conducted a retrospective review of a series of consecutive children who had undergone ETV/ CPC for hydrocephalus over a 1-year period at HBMPM. The primary outcome of interest was time to ETV/ CPC failure. Univariate and multivariate analyses using a Cox proportional hazards regression were performed to identify preoperative factors that were associated with outcomes. RESULTS: Of the 82 children who underwent ETV/ CPC, 52.2% remained shunt free at the last follow-up (mean 6.4 months). On univariate analysis, the ETV success score (ETVSS; p = 0.002), success of the attempted ETV (p = 0.018), and bilateral CPC (p = 0.045) were associated with shunt freedom. In the multivariate models, a lower ETVSS was independently associated with a poor outcome (HR 0.072, 95% CI 0.016-0.32, p < 0.001). Two children (2.4%) died of postoperative seizures. CONCLUSIONS: As in other LMICs, ETV/ CPC is an effective treatment for hydrocephalus in children in Haiti, with a low but significant risk profile. Larger multinational prospective databases may further elucidate the ideal candidate for ETV/ CPC in resource-poor settings.
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Authors | Ashish H Shah, Yudy LaFortune, George M Ibrahim, Iahn Cajigas, Michael Ragheb, Stephanie H Chen, Ernest J Barthélemy, Ariel Henry, John Ragheb |
Journal | Journal of neurosurgery. Pediatrics
(J Neurosurg Pediatr)
Pg. 1-6
(Jan 10 2020)
ISSN: 1933-0715 [Electronic] United States |
PMID | 31923887
(Publication Type: Journal Article)
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