HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Early Radiographic Union Score for Hip Is Predictive of Femoral Neck Fracture Complications Within 2 Years.

AbstractOBJECTIVES:
To determine if the Radiographic Union Score for Hip (RUSH) measured at 3 and 6 months after femoral neck fracture were predictive of reoperation for infection, nonunion, delayed union, avascular necrosis, or implant failure within 24 months of initial surgery.
DESIGN:
Secondary analysis of a randomized controlled trial. Logistic regression was performed to investigate associations between lower RUSH and reoperation. Results were reported as odds ratios (OR), 95% confidence intervals (CIs), and associated P values. All tests were 2 tailed with alpha = 0.05.
SETTING:
Eighty-one clinical sites across 8 countries.
PATIENTS/PARTICIPANTS:
Data from 734 of the clinical trial participants with radiographs at 3 and 6 months after fracture fixation were included.
INTERVENTION:
A reviewer blinded to patients' outcomes independently assigned a RUSH at each follow-up time point.
MAIN OUTCOME MEASURES:
Revision surgery rate related to intervention.
RESULTS:
Lower RUSH at 3 and 6 months were associated with increased odds of reoperation within 24 months of fracture fixation. For every 2-point decrease in RUSH at 3 months, there was a 16% increase in the odds of a patient experiencing a re-operation (OR, 1.16; 95% CI, 1.10-1.22; P < 0.0001). A similar association was observed at the 6-month assessment for every 2-point decrease (OR = 1.05; 95% CI, 1.01-1.09; P = 0.005).
CONCLUSIONS:
Decreased radiographic healing as early as 3 months post fracture fixation is associated with developing patient important femoral neck fracture reoperations. This relationship may guide early treatment decisions, suggesting that 3- and 6-month RUSH are a useful surrogate measure of reoperations within 24 months of fracture fixation.
LEVEL OF EVIDENCE:
Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.
AuthorsMartí Bernaus, Gerard P Slobogean, Sofia Bzovsky, Diane Heels-Ansdell, Qi Zhou, Mohit Bhandari, Marc Swiontkowski, Sheila Sprague, FAITH Investigators
JournalJournal of orthopaedic trauma (J Orthop Trauma) Vol. 34 Issue 6 Pg. e195-e202 (Jun 2020) ISSN: 1531-2291 [Electronic] United States
PMID31809418 (Publication Type: Journal Article, Randomized Controlled Trial)
Topics
  • Femoral Neck Fractures (diagnostic imaging, surgery)
  • Fracture Fixation, Internal
  • Fracture Healing
  • Humans
  • Reoperation
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: