Comparison of two Polygonum chinense varieties used in Chinese cool tea in terms of chemical profiles and antioxidant/anti-inflammatory activities.

Abstract

Despite the extensive use of Polygonum chinense (PC) as a detoxifying ingredient of Chinese cool tea, the efficacy of different PC varieties remains underexplored. Herein, we compare the chemical profiles and antioxidant/anti-inflammatory activities of the aqueous extracts of two PC varieties, namely P. chinense var. chinense (PCC) and P. chinense var. hispidum (PCH). Ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MSMS) and multivariate analysis are used to rapidly identify extract components, while DPPH radical scavenging and xylene-induced mice ear edema assays are used to evaluate antioxidant and anti-inflammatory activities, respectively. Correlation analysis reveals that ellagic acid and quercitrin contents are positively correlated with the magnitude of the anti-inflammatory effect, and the adopted technique is concluded to allow for the rapid discrimination of PC varieties used in Chinese cool tea formulations.

• Authors: Youjiao Wu, Zhifeng Zhang, Tingbo Chen, Chunsong Cheng, Ziling Zhang, Hua Zhou, Pei Luo
• Journal: Food chemistry (Food Chem) Vol. 310 Pg. 125840 (Apr 25 2020) ISSN: 1873-7072 [Electronic] England
• PMID: 31806390 (Publication Type: Comparative Study, Journal Article)
• Copyright: Copyright © 2019 Elsevier Ltd. All rights reserved.

Chemical References

• Anti-Inflammatory Agents
• Antioxidants
• Plant Extracts
• Teas, Herbal
• Xylenes
• Ellagic Acid
• quercitrin
• Quercetin

Topics

• Animals
• Anti-Inflammatory Agents (chemistry, pharmacology)
• Antioxidants (chemistry, pharmacology)
• China
• Chromatography, High Pressure Liquid (statistics & numerical data)
• Ellagic Acid (analysis)
• Food Quality
• Male
• Mice, Inbred BALB C
• Plant Extracts (chemistry)
• Polygonum (chemistry)
• Quercetin (analogs & derivatives, analysis, pharmacology)
• Tandem Mass Spectrometry
• Teas, Herbal (analysis)
• Xylenes (toxicity)