HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

A second puncture and injection technique for treating osteoporotic vertebral compression fractures.

AbstractOBJECTIVE:
To evaluate the clinical effect of the second puncture and injection technique during a percutaneous vertebroplasty (PVP) procedure.
METHODS:
Patients treated with a second puncture and injection (group A) or a single puncture and injection (group B) during PVP at our institution during 2010-2017 were reviewed. Vertebral height loss, visual analogue scale (VAS) score, Oswestry disability index (ODI), adjacent vertebral fractures, and cement leakage were compared between the groups.
RESULTS:
A total of 193 patients were enrolled (86 cases in group A, 107 cases in group B). The follow-up period was 15.64 (12-20) months. The loss of anterior (group A 0.01 ± 0.03; group B 0.14 ± 0.17) and middle (group A 0.13 ± 0.12; group B 0.16 ± 0.11) vertebral height in group B was significantly higher than that in group A (P < 0.05). The VAS score and ODI were also significantly higher in group B than in group A at the final follow-up; the VAS score and ODI in group B were 1.65 ± 0.70 and 14.50 ± 4.16, respectively, and those in group A were 1.00 ± 0.74 and 12.81 ± 4.02, respectively (P < 0.05). Three patients in group A and two in group B experienced adjacent vertebral fractures. Regarding mild, moderate, and severe cement leakage, there were 25 (29%), 5 (5%), and 0 cases, respectively, in group A and 28 (26%), 3 (2.8%), and 1 (0.009%) case, respectively, in group B (P > 0.05).
CONCLUSIONS:
The second puncture and injection technique may effectively increase the dispersion of cement, thus preventing recompression of the cemented vertebral body, and it does not increase the risk of cement leakage or adjacent vertebral fracture.
AuthorsZhaofei Zhang, Feng Jiao, He Huang, Yonghui Feng, Chunliang Xie, Donghua Liu, Fengwei Qin, Sineng Zhang, Peiyu Wu, Weiguang Tan, Wang Tang
JournalJournal of orthopaedic surgery and research (J Orthop Surg Res) Vol. 14 Issue 1 Pg. 413 (Dec 05 2019) ISSN: 1749-799X [Electronic] England
PMID31806033 (Publication Type: Journal Article)
Chemical References
  • Bone Cements
Topics
  • Aged
  • Aged, 80 and over
  • Bone Cements (therapeutic use)
  • Female
  • Follow-Up Studies
  • Fractures, Compression (diagnostic imaging, surgery)
  • Humans
  • Injections
  • Lumbar Vertebrae (diagnostic imaging, injuries, surgery)
  • Male
  • Middle Aged
  • Osteoporotic Fractures (diagnostic imaging, surgery)
  • Punctures (instrumentation, methods)
  • Retrospective Studies
  • Spinal Fractures (diagnostic imaging, surgery)
  • Thoracic Vertebrae (diagnostic imaging, injuries, surgery)
  • Vertebroplasty (instrumentation, methods)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: