Abstract | OBJECTIVE: METHODS: We retrospectively investigated six patients who underwent surgical resection of suspected pulmonary fungal disease prior to allogeneic HSCT between April 2007 and June 2016 at our medical center. RESULTS: We present six patients who underwent surgical resection of suspected pulmonary fungal disease prior to allogeneic HSCT. In our case series, three of four patients who were given a presurgical diagnosis of possible IFD were given a proven diagnosis after surgery, including two cases of invasive aspergillosis (IA) and one case of mucormycosis. All surgeries were performed by video-assisted thoracic surgery (VATS) for lobectomy without major complications. Recurrence of IFD was not observed after allogeneic HSCT in any of the six patients. CONCLUSION: Our experience indicated that surgical resection of persistent localized pulmonary lesions of IFD before allogeneic HSCT was helpful for obtaining a definitive diagnosis and might be useful for reducing recurrence after HSCT.
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Authors | Naonori Harada, Shun-Ichi Kimura, Ayumi Gomyo, Jin Hayakawa, Masaharu Tamaki, Yu Akahoshi, Tomotaka Ugai, Machiko Kusuda, Kazuaki Kameda, Hidenori Wada, Yuko Ishihara, Koji Kawamura, Kana Sakamoto, Miki Sato, Kiriko Terasako-Saito, Misato Kikuchi, Hideki Nakasone, Shinichi Kako, Hiroyoshi Tsubochi, Yoshinobu Kanda |
Journal | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
(J Infect Chemother)
Vol. 26
Issue 2
Pg. 175-180
(Feb 2020)
ISSN: 1437-7780 [Electronic] Netherlands |
PMID | 31735628
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2019. Published by Elsevier Ltd. |
Topics |
- Adult
- Aspergillosis
(complications, surgery)
- Female
- Hematopoietic Stem Cell Transplantation
- Humans
- Invasive Fungal Infections
(complications, surgery)
- Leukemia
(complications, surgery)
- Lung Diseases, Fungal
(complications, surgery)
- Male
- Middle Aged
- Mucormycosis
(complications, surgery)
- Recurrence
- Retrospective Studies
- Thoracic Surgery, Video-Assisted
(methods)
- Transplantation, Homologous
- Young Adult
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