Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon).

Abstract

Nine men with refractory condylomata acuminata were treated with intramuscular interferon alfa-n1 and the effect on their serum lipid levels was noted. Comparison of lipid panels before and after interferon revealed that all nine patients had an increase (median 62 mg/dl, p = 0.004) in their triglyceride level and a decrease (median 21 mg/dl, p = 0.004) in high-density lipoprotein cholesterol levels. Total cholesterol levels tended to decrease but the change was not statistically significant. This effect on serum lipids should be considered when interferon alfa-n1 is used in the treatment of genital warts.

• Authors: E A Olsen, G R Lichtenstein, W E Wilkinson
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 19 Issue 2 Pt 1 Pg. 286-9 (Aug 1988) ISSN: 0190-9622 [Print] United States
• PMID: 3170795 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Cholesterol, HDL
• Cholesterol, LDL
• Cholesterol, VLDL
• Interferon Type I
• Triglycerides
• Cholesterol

Topics

• Cholesterol (blood)
• Cholesterol, HDL (blood)
• Cholesterol, LDL (blood)
• Cholesterol, VLDL (blood)
• Condylomata Acuminata (therapy)
• Humans
• Interferon Type I (pharmacology, therapeutic use)
• Male
• Triglycerides (blood)