Abstract | BACKGROUND: METHODS: We included patient with type hard calcifications. Patients were treated with puncture and lavage followed by injection of STS in the calcification. VAS pain at rest and during activities, ultrasound, and X-ray were evaluated at 1 week and 1 and 3 months. RESULTS: Seventeen patients were included. Baseline VAS at rest and during daily activities was a mean 40.2 ± 25.9 and 65.5 ± 21.6 respectively. All patients underwent the entire procedure with no adverse event. Calcium backflow could be obtained in 15 patients (88.2%). Five patients (30%) had more than 50% decrease of their calcific deposit size at 1 month and 8 (47%) patients at 3 months. VAS pain during activities and at rest decreased significantly at 3 months (p = 0.0004; p = 0.001). Efficacy would be demonstrated if 60% of the patients had more than 50% decrease size of their calcification CONCLUSION: Overall, STS was well tolerated with no side effect occurring during the procedure and the follow-up. However, no significant effect on calcium disappearance could be demonstrated compared with what is expected without STS. New studies using larger volume and repeated injections of STS are now needed. CLINICAL TRIAL REGISTRATION NUMBER:
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Authors | C Darrieurtort-Laffite, A Bertrand-Vasseur, T Garraud, L Planche, B Le Goff |
Journal | Clinical rheumatology
(Clin Rheumatol)
Vol. 39
Issue 2
Pg. 561-569
(Feb 2020)
ISSN: 1434-9949 [Electronic] Germany |
PMID | 31673978
(Publication Type: Clinical Trial, Journal Article)
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Chemical References |
- Chelating Agents
- Thiosulfates
- sodium thiosulfate
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Topics |
- Adult
- Calcinosis
(diagnostic imaging, drug therapy)
- Chelating Agents
(administration & dosage)
- Female
- Humans
- Injections, Intralesional
- Male
- Middle Aged
- Prospective Studies
- Radiography
- Rotator Cuff Injuries
(diagnostic imaging, drug therapy)
- Thiosulfates
(administration & dosage)
- Ultrasonography
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