Viral Hepatitis: Etiology, Epidemiology, Transmission, Diagnostics, Treatment, and Prevention.

Abstract

Viral hepatitis is a major global public health problem affecting hundreds of millions of people and is associated with significant morbidity and mortality. Five major biologically unrelated hepatotropic viruses cause most of the global burden of viral hepatitis. Hepatitis B and hepatitis C are associated with a significant number of chronic infections. Most deaths from viral hepatitis are due to hepatitis B and hepatitis C. An estimated 257 million people were living with HBV and 71 million people were living with HCV. Most people are asymptomatic. New diagnostics and highly effective, pangenotypic direct-acting antivirals provide opportunities to cure and eradicate chronic hepatitis C virus infection.

• Authors: Simone Lanini, Andrew Ustianowski, Raffaella Pisapia, Alimuddin Zumla, Giuseppe Ippolito
• Journal: Infectious disease clinics of North America (Infect Dis Clin North Am) Vol. 33 Issue 4 Pg. 1045-1062 (12 2019) ISSN: 1557-9824 [Electronic] United States
• PMID: 31668190 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
• Copyright: Copyright © 2019 Elsevier Inc. All rights reserved.

Topics

• Global Health
• Hepatitis Viruses (classification, pathogenicity)
• Hepatitis, Viral, Human (epidemiology, prevention & control, therapy, virology)
• Humans