Results of a Multicenter Feasibility Study of an Automated Bedside Glucose Monitoring System in the Burn Intensive Care Setting.

Abstract	Intensive blood glucose regimens required for tight glycemic control in critically ill burn patients carry risk of hypoglycemia and are ultimately limited by the frequency of which serum glucose measurements can be feasibly monitored. Continuous inline glucose monitoring has the potential to significantly increase the frequency of serum glucose measurement. The objective of this study was to assess the accuracy of a continuous glucose monitor with inline capability (Optiscanner) in the burn intensive care setting. A multicenter, observational study was conducted at two academic burn centers. One hundred and six paired blood samples were collected from 10 patients and measured on the Optiscanner and the Yellow Springs Instrument. Values were plotted on a Clarke Error Grid and mean absolute relative difference calculated. Treatment was guided by existing hospital protocols using separately obtained values. 97.2% of results obtained from Optiscanner were within 25% of corresponding Yellow Springs Instrument values and 100% were within 30%. Mean absolute relative difference was calculated at 9.6%. Our findings suggest that a continuous glucose monitor with inline capability provides accurate blood glucose measurements among critically ill burn patients.
Authors	Craig T Elder, Tera Thigpin, Rachel Karlnoski, David Smith, David Mozingo, Joshua S Carson
Journal	Journal of burn care & research : official publication of the American Burn Association (J Burn Care Res) Vol. 41 Issue 3 Pg. 535-538 (05 02 2020) ISSN: 1559-0488 [Electronic] England
PMID	31633750 (Publication Type: Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't)
Copyright	© American Burn Association 2019. All rights reserved. For permissions, please e-mail: [email protected].
Chemical References	Blood Glucose
Topics	Adult Aged Aged, 80 and over Blood Glucose (analysis) Burns (complications) Critical Illness Feasibility Studies Female Florida Humans Hypoglycemia (etiology) Intensive Care Units Male Middle Aged Point-of-Care Testing

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