Efficacy of Curcumin as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients: A Randomized Controlled Clinical Trial.

Abstract

AIM:

The aim of the present study is to evaluate the efficacy of curcumin gel as local drug delivery post-scaling and root planing and its effect on clinical parameters like plaque, gingival scores, pocket depth, and clinical attachment level (CAL).

MATERIALS AND METHODS:

Ten patients with two sites in the contralateral quadrants having probing pocket depths (PPDs) of ≥5 mm were selected. Full-mouth scaling and root planing (SRP) was performed followed by the application of curcumin gel on a single side. Assessment of plaque index (PI), gingival index (GI), PPD, and CALs were done at the baseline and at the 4th week.

RESULTS:

The results revealed that there was a statistically significant reduction in PI and probing depth in the test group when compared with the control group. CAL was improved but the results were not statically significant.

CONCLUSION:

The local application of curcumin gel when used in conjunction with SRP showed a significant improvement in periodontal parameters and has a beneficial effect in patients with chronic periodontitis.

CLINICAL SIGNIFICANCE:

Curcumin gel as an adjunct to SRP showed a marked improvement in restoring gingival health by an improvement in clinical parameters. It has proven properties like anti-inflammatory, antioxidant, antimicrobial, hepatoprotective, immunostimulant, antiseptic, antimutagenic, and it also accelerates wound healing. It may be a more acceptable and viable option for the common man. Curcumin can be used as an effective alternative local drug delivery agent.

• Authors: Kepu V Raghava, Kalyani P Sistla, Sarita J Narayan, Umesh Yadalam, Aditi Bose, Kiran Mitra
• Journal: The journal of contemporary dental practice (J Contemp Dent Pract) Vol. 20 Issue 7 Pg. 842-846 (Jul 01 2019) ISSN: 1526-3711 [Electronic] India
• PMID: 31597806 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Curcumin

Topics

• Chronic Periodontitis
• Curcumin
• Dental Scaling
• Humans
• Male
• Root Planing
• Treatment Outcome