Comparison of computed tomography findings with clinical risks factors for endoscopic therapy in upper gastrointestinal bleeding cases.

Abstract

Several risk scoring systems exist for acute upper gastrointestinal bleeding (UGIB). The clinical Rockall score (clinical RS) and the Glasgow-Blatchford score (GBS) are major risk scores that consider only clinical data. Computed tomography (CT) findings are equivocal in non-variceal UGIB. We compared CT findings with clinical data to predict mortality, rebleeding and need for endoscopic therapy in non-variceal UGIB patients. This retrospective, single-center study included 386 patients admitted to our emergency department with diagnosis of non-variceal UGIB by urgent endoscopy between January 2009 and March 2015. Multivariable logistic regression analysis was used to investigate CT findings and risk factors derived from clinical data. CT findings could not significantly predict mortality and rebleeding in non-variceal UGIB patients. However, upper gastrointestinal hemorrhage in CT findings better predicted the need for endoscopic therapy than clinical data. The adjusted odds ratios were 10.10 (95% CI 5.01-20.40) for clinical RS and 10.70 (95% CI 5.08-22.70) for the GBS. UGI hemorrhage in CT findings could predict the need for endoscopic therapy in non-variceal UGIB patients in our emergency department. CT findings as well as risk score systems may be useful for predicting the need for endoscopic therapy.

• Authors: Fumitake Jono, Hiroshi Iida, Koji Fujita, Megumi Kaai, Kenji Kanoshima, Kanji Ohkuma, Takashi Nonaka, Tomonori Ida, Akihiko Kusakabe, Atsushi Nakamura, Shigeru Koyama, Atsushi Nakajima, Masahiko Inamori
• Journal: Journal of clinical biochemistry and nutrition (J Clin Biochem Nutr) Vol. 65 Issue 2 Pg. 138-145 (Sep 2019) ISSN: 0912-0009 [Print] Japan
• PMID: 31592208 (Publication Type: Journal Article)
• Copyright: Copyright © 2019 JCBNCopyright © 2019 JCBN.