Is reaching 90-90-90 enough to end AIDS? Lessons from Amsterdam.

Abstract

PURPOSE OF REVIEW:

Although cities present opportunities for infectious pathogens such as HIV to spread, public health infrastructure within these cities also provides opportunities to design effective approaches to eliminate transmission of these pathogens. The HIV Transmission Elimination AMsterdam (H-TEAM) Initiative, a consortium of relevant stakeholders involved in HIV prevention and care, designed an integrated approach to curb the HIV epidemic in Amsterdam, including providing preexposure prophylaxis (PrEP), increasing awareness of acute HIV infection, offering same-day test and treat, and improving indicator disease-driven HIV testing.

RECENT FINDINGS:

In 2013, approximately 230 people in Amsterdam were newly diagnosed with HIV, largely belonging to one of two key affected populations, namely MSM and people with a migration background. Since the start of H-TEAM in 2014, a decrease in new diagnoses was observed (130 in 2017), with an increasing proportion of MSM who had been diagnosed with a recent infection.

SUMMARY:

The H-TEAM shows that a city-based concerted effort is feasible. However, major challenges remain, such as reducing the number of late HIV diagnoses, and identifying and providing appropriate services to a diminishing group of individuals who are likely the source of transmission.

• Authors: Godelieve J de Bree, Ard van Sighem, Wim Zuilhof, Jan E A M van Bergen, Maria Prins, Michiel Heidenrijk, Marc van der Valk, Pieter Brokx, Peter Reiss, HIV Transmission Elimination AMsterdam (H-TEAM) Initiative
• Journal: Current opinion in HIV and AIDS (Curr Opin HIV AIDS) Vol. 14 Issue 6 Pg. 455-463 (11 2019) ISSN: 1746-6318 [Electronic] United States
• PMID: 31589173 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Anti-HIV Agents

Topics

• Acquired Immunodeficiency Syndrome (epidemiology, prevention & control, virology)
• Anti-HIV Agents (administration & dosage)
• HIV (drug effects, physiology)
• Humans
• Netherlands (epidemiology)