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Emergence of imipenem-resistant Pseudomonas aeruginosa during treatment of intra-abdominal infection in a patient with ovarian carcinoma.

Abstract
A 59-year-old woman was admitted to the hospital with ovarian carcinoma. After cytoreductive surgery, the patient developed intra-abdominal sepsis. After 17 days of intravenous imipenem, the patient's sputum culture grew imipenem-resistant Pseudomonas aeruginosa. On the 21st day of treatment with imipenem, her peritoneal culture also grew imipenem-resistant Pseudomonas aeruginosa.
AuthorsE H Sze, N G Osborne, M D Adelson, P Granato
JournalJournal of the National Medical Association (J Natl Med Assoc) Vol. 80 Issue 10 Pg. 1133-5 (Oct 1988) ISSN: 0027-9684 [Print] United States
PMID3150461 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Imipenem
Topics
  • Abdomen
  • Drug Resistance, Microbial
  • Emergencies
  • Female
  • Humans
  • Imipenem (therapeutic use)
  • Middle Aged
  • Ovarian Neoplasms (surgery)
  • Pseudomonas Infections (drug therapy)
  • Pseudomonas aeruginosa (drug effects)
  • Surgical Wound Infection (drug therapy)

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