Great efforts have been devoted to exploiting
silicate bioceramics for various applications in soft tissue regeneration, owing to their excellent bioactivity. Based on the inherent ability of
silicate bioceramics to repair tissue, bioactive
ions are easily incorporated into
silicate bioceramics to endow them with extra biological properties, such as enhanced angiogenesis, antibiosis, enhanced osteogenesis, and antitumor effect, which significantly expands the application of multifunctional
silicate bioceramics. Furthermore,
silicate nanobioceramics with unique structures have been widely employed for
tumor therapy. In recent years, the novel applications of
silicate bioceramics for both tissue regeneration and
tumor therapy have substantially grown. Eliminating the skin
tumors first and then repairing the skin
wounds has been widely investigated by our groups, which might shed some light on treating other soft tissue
tumor or
tumor-induced defects. This review first describes the recent advances made in the development of
silicate bioceramics as therapeutic platforms for soft tissue regeneration. We then highlight the major
silicate nanobioceramics used for
tumor therapy.
Silicate bioceramics for both soft tissue regeneration and
tumor therapy are further emphasized. Finally, challenges and future directions of
silicate bioceramics stepping into the clinics are discussed. This review will inspire researchers to create the efficient and functional
silicate bioceramics needed for regeneration and
tumor therapy of other tissues.