Eosinophilic gastroenteritis is a
rare disease that causes various abdominal symptoms that result from the infiltration of eosinophils in the digestive tract. However, this condition has been poorly explored, and the treatment criteria and prognosis
after treatment are still unclear. A 20-year-old man with a refractory
duodenal ulcer had been undergoing treatment since 14 years of age at another hospital. He was admitted to our hospital with
abdominal pain and
anemia (
hemoglobin:6.3g/dL). His blood test showed elevated serum
immunoglobulin E levels, considering that he was allergic to many foods. Furthermore, endoscopic biopsy detected the occurrence of
eosinophilic gastroenteritis with
gastritis,
duodenal ulcer, and
colitis. We treated him by avoiding allergenic foods and prescribing
antihistamine and
vonoprazan;however,
duodenal ulcer and gastrointestinal tract
inflammation did not show improvement. Thus, he was diagnosed with wide-ranging and refractory
eosinophilic gastroenteritis and treated with 40mg/day of
steroids. After 2 months, he recovered from
gastritis and
duodenal ulcer, and his eosinophil level decreased, as assessed using endoscopic biopsy.
Eosinophilic gastroenteritis is poorly investigated, and its treatment standards have not yet been determined. Nonetheless,
steroid treatment is often applied in severe cases.