Hormones and their Structural and Functional Effects on the Brain: How Can We Change our Practice Moving Forward?

Abstract

Is hormone treatment an invasive procedure? In this paper, we discuss aspects related to the choice of treating disorders of sex development (DSD) using hormones. Specifically, we focus on some of the challenging issues related to this treatment and the need to establish a standard of care for the use of hormone therapy in this patient population. The objectives of this paper are to: 1) Enhance understanding of the uncertainties in the decision-making process regarding hormonal interventions to treat patients with DSD. 2) Recognize that the effects of hormonal interventions might require a consent process similar to that applied for surgical procedures. 3) Emphasize the need to establish treatment algorithms that could form the basis of a standard of care for this patient population.

• Authors: Bonnie McCann-Crosby, Laurel Hyle, David Mann, Sheila Gunn, Katherine Flynn, Jennifer Bercaw-Pratt, Oluyemisi Adeyemi, Jennifer Dietrich, Duong Tu, Paul F Austin, V Reid Sutton, Marni Axelrad, Lefkothea Karaviti
• Journal: Pediatric endocrinology reviews : PER (Pediatr Endocrinol Rev) Vol. 16 Issue 4 Pg. 452-456 (Jun 2019) ISSN: 1565-4753 [Print] Israel
• PMID: 31245940 (Publication Type: Journal Article)
• Copyright: Copyright© of YS Medical Media ltd.

Chemical References

• Hormones

Topics

• Brain
• Disorders of Sex Development
• Hormones
• Humans
• Sexual Development