Visual acuity outcomes in Coats disease by classification stage in 160 patients.

Abstract

PURPOSE:

To assess visual outcomes of Coats disease by classification stage.

METHODS:

A retrospective review was conducted on consecutive patients with Coats disease, classified according to Shields classification and with available Snellen visual acuity before and after treatment.

RESULTS:

There were 160 eyes with Coats disease (stage 1 (n=2) vs stage 2A (n=17) vs stage 2B (n=22) vs stage 3A1 (n=26) vs stage 3A2 (n=40) vs stage 3B (n=42) vs stage 4 (n=9) vs stage 5 (n=2)). By comparison, more advanced stage showed greater frequency of poor presenting visual acuity (<20/200) (0% vs 0% vs 50% vs 35% vs 38% vs 83% vs 100% vs 100%, p<0.001) and higher mean intraocular pressure (17 vs 15 vs 15 vs 15 vs 15 vs 15 vs 37 vs 26, p<0.001). More advanced stage was less likely managed with laser photocoagulation (100% vs 87% vs 48% vs 62% vs 74% vs 35% vs 0% vs 0%, p<0.001) and more likely with cryotherapy (0% vs 47% vs 81% vs 81% vs 82% vs 88% vs 50% vs 100%, p=0.001). More advanced stage was associated with lower frequency of visual acuity ≥20/40 (100% vs 71% vs 5% vs 42% vs 23% vs 5% vs 0% vs 0%, p<0.001) and greater frequency of visual acuity <20/200 (0% vs 12% vs 36% vs31 % vs 45% vs 88% vs 0% vs 100%, p<0.001).

CONCLUSION:

Visual acuity in eyes with Coats disease parallels staging with more advanced stage demonstrating poorer visual acuity at presentation and final visit.

• Authors: Carol L Shields, Sanika Udyaver, Lauren A Dalvin, Li-Anne S Lim, Hatice T Atalay, Chloe Khoo, Mehdi Mazloumi, Jerry A Shields
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 104 Issue 3 Pg. 422-431 (03 2020) ISSN: 1468-2079 [Electronic] England
• PMID: 31177186 (Publication Type: Journal Article)
• Copyright: © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Topics

• Adolescent
• Adult
• Aged
• Child
• Child, Preschool
• Female
• Fluorescein Angiography (methods)
• Fundus Oculi
• Humans
• Male
• Middle Aged
• Prognosis
• Retinal Telangiectasis (classification, diagnosis, physiopathology)
• Retrospective Studies
• Severity of Illness Index
• Visual Acuity
• Young Adult