Quality of life after photo-selective vaporization and holmium-laser enucleation of the prostate: 5-year outcomes.

Abstract

This study was aimed to compare serial long-term postoperative changes in quality-of-life (QoL) between photoselective-vaporization (PVP) using 120W-High-Performance-System and holmium-laser-enucleation (HoLEP) in benign-prostatic-hyperplasia (BPH) patients and to identify factors influencing the QoL improvement at the short-term, mid-term and long-term follow-up visits after surgery. We analyzed 1,193 patients with a baseline QoL-index ≥2 who underwent PVP (n = 439) or HoLEP (n = 754). Surgical outcomes were serially compared between the two groups at up to 60-months using the International-Prostatic-Symptom-Score (I-PSS), uroflowmetry, and serum PSA. We used logistic regression analysis to identify predictors of QoL improvement (a reduction in the QoL-index ≥50% compared with baseline) at the short-term (12-months), mid-term (36-months), and long term (60-months) follow-up after surgery. In both groups, the QoL-index was decreased throughout the entire follow-up period compared with that at baseline. There were no significant differences in postoperative changes from the baseline QoL-index between the two groups during the 48-month follow-up, except at 60-months. The degree of improvement in QoL at 60-months after HoLEP was greater than that after PVP. A lower baseline storage-symptom-subscore and a higher bladder-outlet-obstruction-index (BOOI) were independent factors influencing QoL improvement at the short-term. No independent factor influences QoL improvement at the mid- or long-term.

• Authors: Inyoung Sun, Sangjun Yoo, Juhyun Park, Sung Yong Cho, Hyeon Jeong, Hwancheol Son, Seung-June Oh, Jae-Seung Paick, Min Chul Cho
• Journal: Scientific reports (Sci Rep) Vol. 9 Issue 1 Pg. 8261 (06 04 2019) ISSN: 2045-2322 [Electronic] England
• PMID: 31164686 (Publication Type: Journal Article)

Topics

• Aged
• Humans
• Laser Therapy (adverse effects, methods)
• Lasers, Solid-State (adverse effects, therapeutic use)
• Lower Urinary Tract Symptoms (epidemiology, pathology, surgery)
• Male
• Middle Aged
• Postoperative Period
• Prostate (pathology, surgery)
• Prostatic Hyperplasia (epidemiology, pathology, surgery)
• Quality of Life
• Transurethral Resection of Prostate (adverse effects)
• Treatment Outcome