Interventional Treatments for Postherpetic Neuralgia: A Systematic Review.
Abstract | BACKGROUND:
Postherpetic neuralgia, a persistent pain condition often characterized by allodynia and hyperalgesia, is a deleterious consequence experienced by patients after an acute herpes zoster vesicular eruption has healed. The pain associated with postherpetic neuralgia can severely affect a patient's quality of life, quality of sleep, and ability to participate in activities of daily living. Currently, first-line treatments for this condition include the administration of medication therapies such as tricyclic antidepressants, pregabalin, gabapentin, and lidocaine patches, followed by the application of tramadol and capsaicin creams and patches as second- or third-line therapies. As not all patients respond to such conservative options, however, interventional therapies are valuable for those who continue to experience pain. OBJECTIVE: STUDY DESIGN: Systematic review. SETTING: Hospital department in Taiwan. METHODS: Search of PubMed database for all randomized controlled trials regarding postherpetic neuralgia that were published before the end of May 2017. RESULTS: LIMITATIONS: Although few adverse effects were reported, these procedures are invasive, and a careful assessment of the risk-benefit ratio should be conducted prior to administration. CONCLUSION: KEY WORDS:
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Authors | Chia-Shiang Lin, Ying-Chun Lin, Hsuan-Chih Lao, Chien-Chuan Chen |
Journal | Pain physician
(Pain Physician)
Vol. 22
Issue 3
Pg. 209-228
(05 2019)
ISSN: 2150-1149 [Electronic] United States |
PMID | 31151330
(Publication Type: Journal Article, Systematic Review)
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Topics |
- Female
- Humans
- Male
- Neuralgia, Postherpetic
(therapy)
- Pain Management
(methods)
- Randomized Controlled Trials as Topic
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