The International Collaboration on
Cancer Reporting (ICCR) was formed in 2011 to harmonise the datasets, protocols and checklists for pathological reporting of various
cancers and develop internationally agreed upon, evidence-based datasets. A dataset for
prostate cancer in radical
prostatectomy specimens was developed in 2011-2012 as part of a pilot project; however, it required substantial revision following the ISUP Consensus Conference on Gleason Grading in 2014, the publication of the World Health Organisation (WHO) Classification of Tumours of the Urinary System and Male Genital Organs in 2016, and the 8th edition of the Tumour-Node-
Metastasis (TNM) staging system in late 2016. This article presents the up-to-date, evidence-based ICCR dataset and associated commentary for reporting
prostate cancer in radical
prostatectomy specimens. PubMed and Google search engines were used to review the published literature on the subject, and the dataset was developed in line with the previously published ICCR framework for the development of
cancer datasets. Substantial changes have been incorporated into the second edition of the ICCR
prostate cancer (radical
prostatectomy) dataset. These include revisions to
prostate cancer grading, reporting of
intraductal carcinoma of prostate and
surgical margins, among others. Up-to-date
cancer datasets underpin structured reporting and facilitate the production of consistent and accurate pathological data for patient care as well as comparisons between different cohorts and populations internationally.