Increased Gastric MIBG Activity as a Normal Variant.

Abstract

Although increased MIBG activity in the colon is a well-described and well-known normal variant, elevated MIBG activity in the stomach is rarely seen. We describe increased I-MIBG accumulation in the stomach in a 13-year-old girl who had recurrent metastatic neuroblastoma. The activity appeared to be a new MIBG-avid lesion on the planar images. However, the SPECT/CT images revealed that the activity was inside the gastric lumen without anatomical abnormality. On a follow-up I-MIBG scan acquired 3 months later, the stomach no longer had elevated MIBG activity, while the other abnormal activity on prior study remained the same.

• Authors: Xia Bai, Xuemei Wang, Hongming Zhuang
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 44 Issue 9 Pg. 761-763 (Sep 2019) ISSN: 1536-0229 [Electronic] United States
• PMID: 31058691 (Publication Type: Case Reports, Journal Article)

Chemical References

• 3-Iodobenzylguanidine

Topics

• 3-Iodobenzylguanidine (metabolism)
• Adolescent
• Biological Transport
• Female
• Gastric Mucosa (metabolism)
• Humans
• Neoplasm Metastasis
• Neuroblastoma (diagnostic imaging, metabolism, pathology)
• Recurrence
• Single Photon Emission Computed Tomography Computed Tomography
• Stomach (diagnostic imaging, pathology)