Abstract | BACKGROUND: Studies have reported an association between allergy and panic disorder. However, few studies have explored the relationship between allergic rhinitis and panic disorder. Previous studies were limited by cross-sectional study designs, self-reported symptoms, absence of matched controls, and lack of consideration of the influence of steroid and comorbidities. This study aimed to explore the longitudinal association between allergic rhinitis and panic disorder in a large population-based cohort of young people. METHODS: In this study, 79,917 new cases of allergic rhinitis between 1998 and 2012 in individuals younger than 20 years were identified from Taiwan's National Health Insurance Research Database. One control (nonallergic rhinitis) per case ( allergic rhinitis) was randomly selected from the remaining sample, matching for age, sex, residence, and insurance premium. Both groups were followed until the end of 2013 for incidence of panic disorder. Cox regression analysis was performed, adjusting for sex, age, residence, insurance premium, systemic steroids, asthma, atopic dermatitis, allergic conjunctivitis, attention deficit hyperactivity disorder, depression, and Charlson index. RESULTS: LIMITATIONS: Lifestyle, substance use, smoking by the patient or family members, and psychosocial stressors were not evaluated. CONCLUSIONS:
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Authors | Men-Ting Hsieh, Sophie Hsin-Yi Liang, Yao-Hsu Yang, Ting-Yu Kuo, Tsang-Yaw Lin, Tsu-Nai Wang, Vincent Chin-Hung Chen, Meng-Huan Wu |
Journal | Journal of affective disorders
(J Affect Disord)
Vol. 252
Pg. 60-67
(06 01 2019)
ISSN: 1573-2517 [Electronic] Netherlands |
PMID | 30981057
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2019. Published by Elsevier B.V. |
Topics |
- Adolescent
- Age Factors
- Case-Control Studies
- Child
- Child, Preschool
- Cohort Studies
- Comorbidity
- Databases, Factual
- Female
- Humans
- Incidence
- Infant
- Male
- National Health Programs
- Panic Disorder
(epidemiology)
- Regression Analysis
- Rhinitis, Allergic
(epidemiology)
- Risk Factors
- Sex Factors
- Taiwan
(epidemiology)
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