The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis.

Abstract

OBJECTIVES:

Our aim of this study is to compare the efficacy of flupentixol-melitracen in the adjuvant therapy of ulcerative colitis patients in the Chinese population.

METHODS:

Both the RevMan 5.2 and the Stata 12.0 software are used in this study for analysis, and a fixed-effect model (the Mantel-Haenszel method) or a random-effect model (the DerSimonian and Laird method) is used to merge or aggregate the risk ratio (RR) and its 95% confidence intervals (CI) of included studies.

RESULTS:

Eleven trials involving 654 ulcerative colitis patients (treated group: 328; control group: 326) were analyzed in this study. Significant differences (RR = 1.29, 95% CI = 1.20 to 1.40, P < 0.001) between patients were observed between the two groups.

CONCLUSIONS:

Our results suggested that the efficacy of flupentixol-melitracen in the adjuvant therapy of ulcerative colitis is better than traditional drug treatments.

• Authors: Xiaoqian Zhou, Lei Zhao, Ping Yang, Yaxi Chen, Xiong Z Ruan
• Journal: Gastroenterology research and practice (Gastroenterol Res Pract) Vol. 2019 Pg. 3480732 ( 2019) ISSN: 1687-6121 [Print] Egypt
• PMID: 30944561 (Publication Type: Journal Article, Review)