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The Role of MicroRNAs in Hepatoblastoma Tumors.

Abstract
Hepatoblastoma is the most common hepatic malignancy during childhood. However, little is still known about the molecular mechanisms that govern the development of this disease. This review is focused on the recent advances regarding the study of microRNAs in hepatoblastoma and their substantial contribution to improv our knowledge of the pathogenesis of this disease. We show here that miRNAs represent valuable tools to identify signaling pathways involved in hepatoblastoma progression as well as useful biomarkers and novel molecular targets to develop alternative therapeutic strategies in this disease.
AuthorsIon Cristóbal, Marta Sanz-Álvarez, Melani Luque, Cristina Caramés, Federico Rojo, Jesús García-Foncillas
JournalCancers (Cancers (Basel)) Vol. 11 Issue 3 (Mar 22 2019) ISSN: 2072-6694 [Print] Switzerland
PMID30909459 (Publication Type: Journal Article, Review)

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