The first outbreak of measles virus caused by imported genotype D8 in Jiangsu province of China.

Abstract

Here we reported the outbreak of measles cases caused by the genotype D8 measles virus for the first time in Jiangsu province in China, which was possibly imported by a foreign student from Laos. Throat swab specimens were collected, and used to isolate virus. 634-bp fragment of the N gene and 1854-bp fragment of H gene were amplified by reverse transcription-PCR and sequenced, respectively. Phylogenetic results indicated that they belonged to genotype D8 measles virus. Further epidemiology investigation showed that the adults with D8 measles virus infection did not receive measles vaccine before having measles. In China, almost all D8 genotype MeV only infected those population without receiving measles vaccine immunization. Therefore, it is still necessary to implement the supplement activity of measles immunization target adult with immunity gap.

• Authors: Xiuying Deng, Ying Hu, Peishan Lu, Ming-Hao Zhou, Hongxiong Guo
• Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases (Braz J Infect Dis) 2019 Jan - Feb Vol. 23 Issue 1 Pg. 66-69 ISSN: 1678-4391 [Electronic] Brazil
• PMID: 30876879 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2019 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. All rights reserved.

Topics

• Adult
• China (epidemiology)
• Communicable Diseases, Imported (epidemiology, virology)
• Disease Outbreaks
• Female
• Genotype
• Humans
• Measles (epidemiology, virology)
• Measles virus (genetics, isolation & purification)
• Phylogeny