Abstract | BACKGROUND: Adeno-associated viruses (AAVs) have been found in human blood cells, cervical biopsies, and epithelial cell brushings, endometrium, and abortion material, which suggest their possible roles in the induction of miscarriage. OBJECTIVE: In this case control study, the presence of AAV DNA in placental tissue of spontaneous and therapeutic abortions was compared. METHOD: RESULTS: CONCLUSION: There was no statistically significant difference between the presence of the AAV genome in spontaneous and therapeutic abortions. This observation was consistent with other studies in this area.
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Authors | Zahra Sayyadi-Dehno, Seyed Mahmood Seyed Khorrami, Nastaran Ghavami, Fahimeh Ghotbi-Zadeh, Maryam Khushideh, Mostafa Hosseini, Somayeh Shatizadeh Malekshahi, Nazanin-Zahra Shafiei-Jandaghi |
Journal | Fetal and pediatric pathology
(Fetal Pediatr Pathol)
Vol. 38
Issue 3
Pg. 206-214
(Jun 2019)
ISSN: 1551-3823 [Electronic] England |
PMID | 30821558
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Abortion, Spontaneous
(diagnosis, pathology)
- Abortion, Therapeutic
(methods)
- Case-Control Studies
- DNA
(genetics)
- Dependovirus
(genetics, pathogenicity)
- Female
- Humans
- Pathology, Molecular
(methods)
- Polymerase Chain Reaction
(methods)
- Pregnancy
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