Patient-controlled intravenous analgesia with tramadol and lornoxicam after thoracotomy: A comparison with patient-controlled epidural analgesia.

Abstract

To determine efficacy and safety of patient-controlled intravenous analgesia (PCIA) with tramadol and lornoxicam for postoperative analgesia, and its effects on surgical outcomes in patients following thoracotomy.The records of patients who underwent thoracotomy for lung resection between January 2014 and December 2014 at our institution were reviewed. The patients were divided into 2 groups according to postoperative pain treatment modalities. Patients of the patient-controlled epidural analgesia (PCEA) group (n = 63), received PCEA with 0.2% ropivacaine plus 0.5 μg/mL sufentanil, while patients in the PCIA group (n = 48), received PCIA with 5 mg/mL tramadol and 0.4 mg/mL lornoxicam. Data were collected for the quality of pain control, incidences of analgesia related side effects and pulmonary complications, lengths of thoracic intensive care unit stay and postoperative hospital stay, and in-hospital mortality.Pain at rest was always controlled well in both groups during the 4-day postoperative period. Patients in the PCIA group reported significantly higher pain scores on coughing and during mobilization in the first 2 postoperative days. The incidences of side effects and pulmonary complications, in-hospital mortality and other outcomes were similar between groups.PCIA with tramadol and lornoxicam can be considered as a safe and effective alternative with respect to pain control and postoperative outcomes for patients underwent thoracotomy.

• Authors: Juying Jin, Su Min, Qibin Chen, Dong Zhang
• Journal: Medicine (Medicine (Baltimore)) Vol. 98 Issue 7 Pg. e14538 (Feb 2019) ISSN: 1536-5964 [Electronic] United States
• PMID: 30762794 (Publication Type: Journal Article, Observational Study)

Chemical References

• Analgesics, Opioid
• Anti-Inflammatory Agents, Non-Steroidal
• Piroxicam
• Tramadol
• Ropivacaine
• Sufentanil
• lornoxicam

Topics

• Adult
• Age Factors
• Aged
• Analgesia, Epidural (adverse effects, methods)
• Analgesia, Patient-Controlled (adverse effects, methods)
• Analgesics, Opioid (administration & dosage, adverse effects)
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage, adverse effects)
• Female
• Hospital Mortality
• Humans
• Length of Stay
• Male
• Middle Aged
• Pain Measurement
• Pain, Postoperative (drug therapy)
• Piroxicam (administration & dosage, adverse effects, analogs & derivatives)
• Postoperative Complications (epidemiology)
• Respiratory Function Tests
• Ropivacaine (administration & dosage, adverse effects)
• Sex Factors
• Sufentanil (administration & dosage, adverse effects)
• Thoracotomy
• Tramadol (administration & dosage, adverse effects)