Abstract |
A mitochondria-targeted ratiometric fluorescent probe based on hemicyanine and pyrido[1,2-a] benzimidazole was presented. It shows high sensitivity and selectivity toward SO2 in pure water. The limit of detection (LOD) was as low as 26.7 nM, which is superior to most reported probes. Most importantly, the probe was successfully used for fluorescence imaging of endogenous bisulfite in mitochondria in Glioma cells.
|
Authors | Guangle Song, Aikun Liu, Hongli Jiang, Ruixue Ji, Jian Dong, Yanqing Ge |
Journal | Analytica chimica acta
(Anal Chim Acta)
Vol. 1053
Pg. 148-154
(Apr 11 2019)
ISSN: 1873-4324 [Electronic] Netherlands |
PMID | 30712560
(Publication Type: Journal Article)
|
Copyright | Copyright © 2018 Elsevier B.V. All rights reserved. |
Chemical References |
- Fluorescent Dyes
- Sulfur Dioxide
|
Topics |
- Cell Line, Tumor
- Fluorescence Resonance Energy Transfer
(methods)
- Fluorescent Dyes
(metabolism)
- Humans
- Kinetics
- Limit of Detection
- Mitochondria
(metabolism)
- Optical Imaging
- Sulfur Dioxide
(chemistry, metabolism)
|