Abstract |
A chemiresistive sensor is described for the lung cancer biomarker hexanal. A composite consisting of molecularly imprinted polymer nanoparticles and multiwalled carbon nanotubes was used in the sensor that is typically operated at a voltage of 4 V and is capable of selectively sensing gaseous hexanal at room temperature. It works in the 10 to 200 ppm concentration range and has a 10 ppm detection limit (at S/N = 3). The sensor signal recovers to a value close to its starting value without the need for heating even after exposure to relatively high levels of hexanal. Graphical abstract Schematic presentation of a chemiresistive sensor for detection of hexanal, a cancer biomarker. The hexanal-imprinted polymeric nanoparticles were synthesized, mixed with multiwalled carbon nanotubes and coated on the surface of an interdigitated electrode to produce a nanocomposite chemiresistor gas sensor for hexanal.
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Authors | Sajjad Janfaza, Maryam Banan Nojavani, Maryam Nikkhah, Taher Alizadeh, Ali Esfandiar, Mohammad Reza Ganjali |
Journal | Mikrochimica acta
(Mikrochim Acta)
Vol. 186
Issue 3
Pg. 137
(02 01 2019)
ISSN: 1436-5073 [Electronic] Austria |
PMID | 30707323
(Publication Type: Journal Article)
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Chemical References |
- Aldehydes
- Biomarkers, Tumor
- Gases
- Methacrylates
- Nanotubes, Carbon
- Volatile Organic Compounds
- methacrylic acid
- Polymethyl Methacrylate
- n-hexanal
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Topics |
- Aldehydes
(analysis)
- Biomarkers, Tumor
(analysis)
- Biosensing Techniques
- Electrochemical Techniques
- Electrodes
- Gases
(chemistry)
- Humans
- Limit of Detection
- Lung Neoplasms
(diagnosis)
- Methacrylates
(chemistry)
- Molecular Imprinting
- Nanocomposites
(chemistry)
- Nanoparticles
(chemistry)
- Nanotubes, Carbon
(chemistry)
- Particle Size
- Polymerization
- Polymethyl Methacrylate
(chemistry)
- Surface Properties
- Temperature
- Volatile Organic Compounds
(analysis)
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