Modulation of temporal resolution and speech long-latency auditory-evoked potentials by transcranial direct current stimulation in children and adolescents with dyslexia.

Abstract

In recent years, transcranial direct current stimulation (tDCS) has been used as a safe and non-invasive method for children and adolescents with dyslexia. Our aim in this study was to investigate the effect of tDCS on variables of temporal resolution and speech long-latency auditory-evoked potentials with two electrode arrays on superior temporal gyrus (STG). A total of 17 children and adolescents with dyslexia (age 9-12 years) were included in our study. All participants underwent the gap in noise (GIN) test and long-latency auditory-evoked potentials recording at baseline without applying tDCS, sham (placebo), and after 20 min of exposure to two different tDCS polarities: anode of tDCS on left STG/cathode on the right shoulder and anode on the left STG/cathode on right STG to enhance left lateralization. Our results showed significant decreases in the threshold value and increases in the percentages of correct responses in the GIN test. We also found reduced latency and increased amplitude of the P1, N1, and P2 waves in two stimulation polarities compared with baseline and sham. Our findings indicate the potential role of tDCS on improving the characteristics of central auditory processing, especially temporal information processing in children and adolescents with dyslexia, and could introduce a new strategy to facilitate the rehabilitation of central auditory processing disorders in future.

• Authors: Vida Rahimi, Ghassem Mohamadkhani, Javad Alaghband-Rad, Fatemeh Ranjbar Kermani, Hossien Nikfarjad, Saman Marofizade
• Journal: Experimental brain research (Exp Brain Res) Vol. 237 Issue 3 Pg. 873-882 (Mar 2019) ISSN: 1432-1106 [Electronic] Germany
• PMID: 30635704 (Publication Type: Journal Article)

Topics

• Adolescent
• Auditory Perception (physiology)
• Child
• Dyslexia (physiopathology)
• Electroencephalography
• Evoked Potentials, Auditory (physiology)
• Female
• Humans
• Male
• Temporal Lobe (physiopathology)
• Time Perception (physiology)
• Transcranial Direct Current Stimulation (methods)