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Salvage laryngectomy following organ-preservation therapy - An evidence-based review.

Abstract
Salvage total laryngectomy is often indicated in patients with recurrent or persistent laryngeal cancer after radiation or chemoradiation treatment. This article reviews and discusses key considerations regarding salvage laryngectomy. Within this article, a review of the salvage laryngectomy incidence in the major organ preservation trials, survival rates, predictors of outcomes, complication rates, and the roles of elective neck dissection and free tissue transfer for reconstruction in patients undergoing salvage laryngectomy is provided.
AuthorsDustin A Silverman, Sidharth V Puram, James W Rocco, Matthew O Old, Stephen Y Kang
JournalOral oncology (Oral Oncol) Vol. 88 Pg. 137-144 (01 2019) ISSN: 1879-0593 [Electronic] England
PMID30616784 (Publication Type: Journal Article, Review)
CopyrightCopyright © 2018 Elsevier Ltd. All rights reserved.
Topics
  • Chemoradiotherapy (adverse effects)
  • Deglutition
  • Humans
  • Laryngeal Neoplasms (mortality, therapy)
  • Laryngectomy (adverse effects, methods)
  • Neck Dissection (adverse effects)
  • Patient Compliance
  • Postoperative Complications
  • Plastic Surgery Procedures
  • Respiratory Tract Fistula (etiology)
  • Risk Factors
  • Salvage Therapy (methods)
  • Speech
  • Surgical Flaps
  • Survival Rate
  • Voice

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