Abstract |
Constraint-induced movement therapy (CI therapy) has been shown to reduce disability for individuals with upper extremity (UE) hemiparesis following different neurologic injuries. This article describes the study design and methodological considerations of the Bringing Rehabilitation to American Veterans Everywhere (BRAVE) Project, a randomized controlled trial of CI therapy to improve the motor deficit of participants with chronic and subacute traumatic brain injury. Our CI therapy protocol comprises 4 major components: (1) intensive training of the more-affected UE for target of 3 hour/day for 10 consecutive weekdays, (2) a behavioral technique termed shaping during training, (3) a "transfer package," 0.5 hour/day, of behavioral techniques to transfer therapeutic gains from the treatment setting to the life situation, and (4) prolonged restraint of use of the UE not being trained. The primary endpoint is posttreatment change on the Motor Activity Log, which assesses the use of the more-affected arm outside the laboratory in everyday life situations. Data from a number of secondary outcome measures are also being collected and can be categorized as physical, genomic, biologic, fitness, cognitive/behavioral, quality of life, and neuroimaging measures.
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Authors | David M Morris, Edward Taub, Victor W Mark, Wei Liu, Lisa Brenner, Treven Pickett, Kelly Stearns-Yoder, Staci Bishop-McKay, Andrea Taylor, Laura Reder, Terrie Adams, James Rimmer, Dustin Dew, Jerzy Szaflarski, Brent Womble, Lillian Stevens, David Rothman, Gitendra Uswatte |
Journal | The Journal of head trauma rehabilitation
(J Head Trauma Rehabil)
2019 Jul/Aug
Vol. 34
Issue 4
Pg. 268-279
ISSN: 1550-509X [Electronic] United States |
PMID | 30608308
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, U.S. Gov't, Non-P.H.S.)
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Topics |
- Adult
- Arm
(innervation)
- Arm Injuries
(rehabilitation)
- Behavior Therapy
- Brain Injuries, Traumatic
(rehabilitation)
- Combined Modality Therapy
- Disability Evaluation
- Humans
- Nervous System Diseases
(rehabilitation)
- Paresis
(rehabilitation)
- Physical Therapy Modalities
- Quality of Life
- Transfer, Psychology
- United States
- Veterans
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