Instantaneous restoration of cardiac output by noninvasive positive pressure ventilation in a patient with obesity hypoventilation syndrome.

Abstract

We report a 30-year-old man with severe obesity hypoventilation syndrome (OHVS) complicated by right-sided heart failure. Polysomnography revealed severe obstructive sleep apnea with apnea-hypopnea index (AHI) 70.4/h and gradual decrease in minimum oxygen saturation (SpO2) from 86% before sleep to 36% during sleep. Cardiac output (CO) was suppressed from 3.9 L/min before sleep to 2.5 L/min during sleep. Noninvasive positive pressure ventilation (NPPV) treatment drastically restored CO to the level before sleep, and improved AHI to 9.4/h and minimum SpO2 to 87%. NPPV may provide rapid and powerful symptom relief in patients with OHVS complicated with right sided heart failure.

• Authors: Masayoshi Yoshida, Shin-Ichi Ando, Toshiaki Kadokami, Sumito Narita, Hidetoshi Momii, Yumi Sato, Tomoko Kiyokawa, Chikako Nakao
• Journal: Journal of cardiology cases (J Cardiol Cases) Vol. 3 Issue 1 Pg. e40-e42 (Feb 2011) ISSN: 1878-5409 [Electronic] Japan
• PMID: 30532832 (Publication Type: Journal Article)