Abstract | BACKGROUND: PATIENTS AND METHODS: Sixty patients with localized non-segmental stable vitiligo were assigned randomly and equally into groups. Patients subjected to intradermal injection of either fluorouracil (50 mg/mL), triamcinolone acetonide (3 mg/mL) or an equal mixture of both drugs. All patients had four treatment sessions every 2 weeks were followed up for 6 months. RESULTS: Intradermal fluorouracil showed the best overall improvement (median 52.27, IQR 36.25-68.18) when compared with triamcinolone (median 13.86, IQR 3.83-33.32) and the drug mixture (median 17.15, IQR 7.48-41.67). During follow-up, the vitiliginous patches continued to repigment for 6 months in fluorouracil and the drug mixture groups. The improvement stopped 1 month after the last session in the triamcinolone group. CONCLUSION:
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Authors | Hatem Abo-El-Wafa Zohdy, Mohamed Saber Hussein |
Journal | Journal of cosmetic dermatology
(J Cosmet Dermatol)
Vol. 18
Issue 5
Pg. 1430-1434
(Oct 2019)
ISSN: 1473-2165 [Electronic] England |
PMID | 30444065
(Publication Type: Journal Article)
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Copyright | © 2018 Wiley Periodicals, Inc. |