Abstract |
A recent study used CRISPR/Cas9 to reveal long-range looping between disease-related genes and their regulatory elements that is mediated by the CCCTC-binding factor (CTCF) in prostate cancer.
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Authors | Xiang Guo, Ann Dean |
Journal | Genome biology
(Genome Biol)
Vol. 19
Issue 1
Pg. 185
(11 06 2018)
ISSN: 1474-760X [Electronic] England |
PMID | 30400943
(Publication Type: Journal Article, Research Support, N.I.H., Intramural)
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Chemical References |
- CCCTC-Binding Factor
- CTCF protein, human
- Chromatin
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Topics |
- CCCTC-Binding Factor
(genetics, metabolism)
- CRISPR-Cas Systems
- Chromatin
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Prostatic Neoplasms
(genetics, pathology)
- Protein Binding
- Regulatory Elements, Transcriptional
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