Abstract | RATIONALE: PATIENT CONCERNS: A 76-year-old man with dysphagia presented to a local clinic. Gastrointestinal endoscopy revealed a polypoid tumor in the middle esophagus and he was referred to our hospital. DIAGNOSIS AND INTERVENTIONS: OUTCOMES: The patient showed complete response within 4 cycles of chemotherapy. However, the disease recurred 5.5 months after the final course of EP chemotherapy. LESSONS: A therapeutic strategy based on assessment of which component caused metastasis might be important for metastatic carcinosarcoma comprising 3 components, although more accumulation of data about the efficacy of chemotherapy is necessary. Moreover, elucidation of the mechanisms underlying generation of carcinosarcoma is expected in the future.
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Authors | Kenji Tsuchihashi, Shuji Arita, Minako Fujiwara, Kazuhide Iwasaki, Atsushi Hirano, Tomoyasu Yoshihiro, Kenta Nio, Yutaka Koga, Motohiro Esaki, Hiroshi Ariyama, Hitoshi Kusaba, Taiki Moriyama, Kenoki Ohuchida, Eishi Nagai, Masafumi Nakamura, Yoshinao Oda, Koichi Akashi, Eishi Baba |
Journal | Medicine
(Medicine (Baltimore))
Vol. 97
Issue 41
Pg. e12796
(Oct 2018)
ISSN: 1536-5964 [Electronic] United States |
PMID | 30313107
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Biomarkers, Tumor
- Carcinoma, Neuroendocrine
(drug therapy, pathology)
- Carcinosarcoma
(drug therapy, pathology)
- Esophageal Neoplasms
(drug therapy, pathology)
- Humans
- Male
- Neoplasm Metastasis
- Neoplasm Recurrence, Local
- Neoplasm Staging
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