Valve-Sparing Root Replacement Provides Excellent Midterm Outcomes for Bicuspid Valve Aortopathy.

Abstract

BACKGROUND:

Standard therapy for aortic root dilation in the setting of bicuspid aortic valves remains use of a composite valve conduit. The long-term durability of valve-sparing root replacement (VSRR) in bicuspid aortopathy is presently unclear. In this study, the midterm results of performing VSRR in the setting of a bicuspid valve was analyzed.

METHODS:

A single institutional database identified 280 patients who underwent VSRR from 2005 to 2016. Outcomes were analyzed in 60 consecutive patients undergoing a VSRR in the setting of a bicuspid aortic valve with aortic insufficiency (AI). Patients were followed prospectively and had annual echocardiograms.

RESULTS:

The average age in this series was 42 ± 11 years. Eighty percent were men and 33% had New York Heart Association class III to IV symptoms. More than 2+ AI was present in 42% of patients preoperatively. The incidence of operative death, stroke, and renal failure was 0%. Mean follow-up was 39 ± 30 months. At latest follow-up, 62% of patients had zero AI and 87% of patients had <1+ AI. At 5 years, freedom from >2+ AI was 97% and freedom from AVR was 96%. Preoperative AI was not found to be a significant risk factor for postoperative >2+ AI (p = 0.61) or AVR (p = 0.61).

CONCLUSIONS:

VSRR can be safely and effectively performed in young patients with bicuspid valve anatomy regardless of degree of preoperative AI. Valve function is durable and the incidence of valve-related complications is low. VSRR is an attractive and potentially superior option to conventional root replacement in appropriately selected patients with bicuspid aortopathy.

• Authors: Michael O Kayatta, Bradley G Leshnower, LaRonica McPherson, Jose N Binongo, Yi Lasanajak, Edward P Chen
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 107 Issue 2 Pg. 499-504 (02 2019) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 30292845 (Publication Type: Journal Article)
• Copyright: Copyright © 2019 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Topics

• Adult
• Aortic Valve (abnormalities, surgery)
• Bicuspid Aortic Valve Disease
• Echocardiography
• Female
• Follow-Up Studies
• Georgia (epidemiology)
• Heart Valve Diseases (diagnosis, surgery)
• Heart Valve Prosthesis Implantation (methods)
• Humans
• Incidence
• Male
• Postoperative Complications (epidemiology)
• Retrospective Studies
• Survival Rate (trends)
• Time Factors
• Treatment Outcome