Primary Vitreoretinal Lymphoma Presenting as a Posterior Capsule Plaque.

Abstract

Primary vitreoretinal lymphoma (PVRL) can be a diagnostic challenge and commonly presents as a partially steroid-responsive vitritis or as subretinal cream-colored infiltrates. The authors present a patient with PVRL who initially presented with bilateral vitritis; however, after two non-diagnostic vitrectomy specimens and two unremarkable brain MRIs, she was lost to follow-up. She presented 2.5 years later with a white plaque on the posterior capsule of her left intraocular lens, though the vitreous cavity was free of infiltrate. Repeat biopsy revealed diffuse large B-cell lymphoma, and brain MRI demonstrated an enhancing lesion of the cerebellum, consistent with primary central nervous system lymphoma.

• Authors: Rehan M Hussain, Robert B Garoon, Jay S Duker, Sander R Dubovy, Thomas A Albini
• Journal: Ophthalmic surgery, lasers & imaging retina (Ophthalmic Surg Lasers Imaging Retina) Vol. 49 Issue 9 Pg. 732-734 (09 01 2018) ISSN: 2325-8179 [Electronic] United States
• PMID: 30222812 (Publication Type: Case Reports, Journal Article, Video-Audio Media)
• Copyright: Copyright 2018, SLACK Incorporated.

Topics

• Aged
• Biopsy
• Diagnosis, Differential
• Female
• Humans
• Lymphoma, Large B-Cell, Diffuse (diagnosis, surgery)
• Retinal Neoplasms (diagnosis, surgery)
• Tomography, Optical Coherence (methods)
• Vitrectomy (methods)
• Vitreous Body (pathology)