Source-specific lung cancer risk assessment of ambient PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) in central Tehran.

Abstract

In this study, source-specific cancer risk characterization of ambient PM2.5-bound polycyclic aromatic hydrocarbons (PAHs) was performed in central Tehran. The positive matrix factorization (PMF) model was applied for source apportionment of PAHs in the area from May 2012 through May 2013. The PMF runs were carried out using chemically analyzed PAHs mass concentrations. Five factors were identified as the major sources of airborne PAHs in central Tehran, including petrogenic sources and petroleum residue, natural gas and biomass burning, industrial emissions, diesel exhaust emissions, and gasoline exhaust emissions, with approximately similar contributions of around 20% to total PAHs concentration from each factor. Results of the PMF source apportionment (i.e., PAHs factor profiles and contributions) were then used to calculate the source-specific lung cancer risks for outdoor and lifetime exposure, using the benzo[α]pyrene (BaP) equivalent method. Our risk assessment analysis indicated that the lung cancer risk associated with each specific source is within the range of 10-6-10-5, posing cancer risks exceeding the United States Environmental Protection Agency's (USEPA) guideline safety values (10-6). Furthermore, the epidemiological lung cancer risk for lifetime exposure to total ambient PAHs was found to be (2.8 ± 0.78) × 10-5. Diesel exhaust and industrial emissions were the two sources with major contributions to the overall cancer risk, contributing respectively to 39% and 27% of the total risk associated with exposure to ambient PAHs. Results from this study provide an estimate of the cancer risk caused by exposure to ambient PAHs in highly crowded areas in central Tehran, and can be used as a guide for the adoption of effective air quality policies in order to reduce the human exposure to these harmful organic species.

• Authors: Sina Taghvaee, Mohammad H Sowlat, Mohammad Sadegh Hassanvand, Masud Yunesian, Kazem Naddafi, Constantinos Sioutas
• Journal: Environment international (Environ Int) Vol. 120 Pg. 321-332 (11 2018) ISSN: 1873-6750 [Electronic] Netherlands
• PMID: 30107293 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2018. Published by Elsevier Ltd.

Chemical References

• Air Pollutants
• Particulate Matter
• Petroleum
• Polycyclic Aromatic Hydrocarbons
• Vehicle Emissions

Topics

• Air Pollutants (analysis)
• Cities
• Environmental Monitoring
• Humans
• Industry
• Iran
• Lung Neoplasms
• Particulate Matter (analysis)
• Petroleum
• Polycyclic Aromatic Hydrocarbons (analysis)
• Risk Assessment
• Vehicle Emissions