Patterns of Carriage of Prescribed Adrenaline Autoinjectors in 10- to 14-Year-Old Food-Allergic Students: A Population-Based Study.

Abstract

BACKGROUND:

Adolescence is well recognized as a period of increased risk for severe and fatal food-induced anaphylaxis. Current Australian adrenaline autoinjector (AAI) prescription guidelines therefore suggest that consideration be given to AAI prescription in all adolescents with a food allergy. To date, however, few studies have assessed the AAI carriage behavior of adolescents prescribed AAI devices.

OBJECTIVE:

To determine the carriage behavior of prescribed AAI devices in a population-based sample of young Australian adolescents.

METHODS:

Students aged 10 to 14 years (and their parents) from randomly selected schools in metropolitan Melbourne completed self-administered questionnaires regarding the history and management of food allergy, including prescription and carriage of AAI device in different domains of school and social life.

RESULTS:

A total of 9816 students completed the questionnaire (46% response): 620 students were assessed to have likely IgE-mediated food allergy and 234 (38%) of these had been prescribed an AAI. Most students (93%; 95% CI, 89%-96%) who were prescribed AAIs reported that they provided their AAI and anaphylaxis action plan to their school. Adherence to AAI carriage in other domains of social life was poor, with 49% (95% CI, 42%-56%) never carrying their AAI in 1 or more locations. Carriage of the AAI device was particularly poor when students were independent of parental supervision: 32% (95% CI, 25%-39%) never carried it when they were by themselves, 28% (95% CI, 22%-36%) never carried it while out with friends, and 36% (95% CI, 30%-43%) never carried their AAI to sporting activities.

CONCLUSIONS:

Carriage of AAI devices is suboptimal in young adolescents prescribed AAIs, particularly when young adolescents are independent of parental supervision.

• Authors: Marnie Robinson, Jennifer J Koplin, Michael J Field, Mari Sasaki, Rachel L Peters, Vicki McWilliam, Susan M Sawyer, George C Patton, Peter J Vuillermin, Jo Douglass, Lyle C Gurrin, Mimi L K Tang, Shyamali C Dharmage, Katrina J Allen, SchoolNuts Investigators
• Journal: The journal of allergy and clinical immunology. In practice (J Allergy Clin Immunol Pract) Vol. 7 Issue 2 Pg. 437-443 (02 2019) ISSN: 2213-2201 [Electronic] United States
• PMID: 30031901 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2018 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Chemical References

• Epinephrine

Topics

• Adolescent
• Anaphylaxis (drug therapy, etiology)
• Australia
• Child
• Epinephrine (administration & dosage)
• Female
• Food Hypersensitivity (complications)
• Health Behavior
• Humans
• Injections (instrumentation)
• Male
• Self Administration (instrumentation)
• Students