Abstract | BACKGROUND: AIMS: METHODS: Eighty children (aged 3-7 years) were randomly assigned to either the control group (group C; intraoperative remifentanil infusion) or the intervention group (group R; intraoperative remifentanil infusion followed by remifentanil maintenance during the recovery phase). Intraoperative remifentanil infusion (0.2 μg/kg/min) was discontinued upon surgery completion in the group C, and was maintained until the discharge criteria were met at a dose of 0.05 μg/kg/min in the group R. The incidence of emergence delirium was assessed using a five-point agitation scale and the Pediatric Anesthesia Emergence Delirium scale after arrival in the postanesthesia care unit. Postoperative pain was assessed using the Children's Hospital of Eastern Ontario Pain Scale. RESULTS: The incidence of emergence delirium according to the five-point agitation scale (scores ≥ 4) was lower in the group R (33.3%) compared to the group C (68.3%) (odds ratio 0.206; 95% CI 0.080 to 0.531; P = 0.002). Similar results were obtained using the Pediatric Anesthesia Emergence Delirium scale (scores > 12), with an incidence of 5.1% in the group R and 34.0% in the control group (odds ratio 0.104; 95% CI 0.022 to 0.497; P = 0.001). The Children's Hospital of Eastern Ontario Pain Scale scores and occurrence of postoperative adverse events including laryngospasm, desaturation, nausea, and vomiting were similar between the two groups. CONCLUSION:
|
Authors | Eun Kyung Choi, Shiback Lee, Won Jae Kim, Sang-Jin Park |
Journal | Paediatric anaesthesia
(Paediatr Anaesth)
Vol. 28
Issue 8
Pg. 739-744
(08 2018)
ISSN: 1460-9592 [Electronic] France |
PMID | 30004624
(Publication Type: Journal Article, Randomized Controlled Trial)
|
Copyright | © 2018 John Wiley & Sons Ltd. |
Chemical References |
- Analgesics, Opioid
- Anesthetics
- Anesthetics, Inhalation
- Sevoflurane
- Remifentanil
|
Topics |
- Analgesics, Opioid
(administration & dosage)
- Anesthesia Recovery Period
- Anesthetics
(administration & dosage)
- Anesthetics, Inhalation
(adverse effects)
- Child
- Child, Preschool
- Consciousness Monitors
- Emergence Delirium
(chemically induced, drug therapy)
- Female
- Humans
- Male
- Perioperative Care
(methods)
- Postoperative Care
(methods)
- Remifentanil
(administration & dosage)
- Sevoflurane
(adverse effects)
- Strabismus
(surgery)
- Treatment Outcome
|